Moderate anatomical abnormalities of climbing fiber innervation of tippy mutant Purkinje cells were not associated with changes in climbing fiber-EPSC amplitudes.
Although the cerebellum shows grossly normal foliation, tippy mutants display a complex cerebellar Purkinje cell phenotype consisting of abnormal dendritic branching with immature spine features and patchy, non-apoptotic cell death that is associated with widespread dystrophy and degeneration of the Purkinje cell axons throughout the white matter, the cerebellar nuclei and the vestibular nuclei. Homozygous tippy mutant mice are small, ataxic and die around weaning. This mysterious event is only known to Chino and her father.This study represents the first detailed analysis of the spontaneous neurological mouse mutant, tippy, uncovering its unique cerebellar phenotype. As Chino's grandfather passed away, his "soul" somehow transffered into Tippy's body, their rabbit, and has been living in it since then. Tippy's "soul" is Chino's grandfather, it is speculated that this was Cocoa's doing since when she was younger she used a "spell" on him in which she said that he shall reborn as a rabbit in his next life.In Chapter 20, Tippy, alongside Chino Kafuu, greeted Marcus "The Kane" McGee and Karizza Stronghold in the Rabbit House and led them to a table. XP4 Fanfics XP4 Heroes Coalition - Neo-City Diaries Despite being most likely really old, Tippy acts far more childish compared to his son. However, in the 2nd season, Cocoa and Chiya somehow knew that he could talk and asked him to "read their coffee fortunes". Only Chino and her father know he is able to talk (at the end of the season 1). Tippy acts as a little companion for Chino and her friends. She has the personality of Chino's grandfather and his memories, meaning he's kept skills he had when he was alive, unfortunately he's only retained abilities, his new rabbit-vessel can handle, like giving life advice at needed moments. She is female, although her body is inhabited by the soul and conscience of Chino's grandfather. 3.1 XP4 Heroes Coalition - Neo-City Diaries.
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